Cold Agglutinins and Cryoglobulins Associate With Clinical and Laboratory Parameters of Cold Urticaria

Platelet cold agglutinins.

A “cold” platelet agglutinin is described reacts only at temperatures below 34#{176}C. which is present in plasma and serum, It agglutinates homologous and autois greater than 100,000 in molecular logous platelets but appears to have no weight, appears to be a protein of the imeffect on in vivo platelet function. It is munoglobulin type, is adsorbed by plateseen in patients with systemic diseas...

Clinical features and anaphylaxis in children with cold urticaria.

OBJECTIVE To characterize the features of cold urticaria in children, with particular focus on systemic reactions, because little pediatric data are available. METHODOLOGY Chart reviews of 30 children <18 years old who were evaluated in the past 3 years at the Children's Hospital Allergy Program (Boston, MA) and a private allergy practice. Demographic, diagnostic, and therapeutic data were co...

How I manage cold agglutinins.

From the Department of Pathology, University of Michigan Medical Center, Ann Arbor, Michigan. Address reprint requests to: W. John Judd, FIBMS, MIBiol, Professor of Immunohematology, Department of Pathology, UH-2G332, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0054; e-mail: [email protected]. Received for publication November 2, 2005; accepted No...

Cold urticaria and celiac disease.

Cold urticaria can be associated with blood and thyroid disorders, drugs, or infections. Celiac disease is an autoimmune enteropathy caused by permanent gluten intolerance. It is often associated with other autoimmune diseases, such as chronic idiopathic urticaria. Nevertheless, association with cold urticaria has not yet been described. A boy aged 3 years 8 months presented local urticaria-ang...

Cold Agglutinins. v. Deterioration of Cold Isohemagglutinins on Storage.